NSAIDS and the microcirculation of the stomach

Gastroenterol Clin North Am. 1996 Jun;25(2):299-315. doi: 10.1016/s0889-8553(05)70248-x.

Abstract

In this article, the effect of NSAIDs on the gastric mucosal microcirculation was reported. Although the precise mechanism of NSAID-induced ulcerogenesis is still unknown, most NSAIDs have been shown to impair gastric mucosal microcirculation and cause gastric mucosal damage.

Publication types

  • Review

MeSH terms

  • Animals
  • Anti-Inflammatory Agents, Non-Steroidal / pharmacology*
  • Blood Flow Velocity
  • Gastric Mucosa / blood supply*
  • Gastric Mucosa / drug effects
  • Gastroscopy
  • Humans
  • Indomethacin / pharmacology
  • Microcirculation / drug effects
  • Phenylpropionates / pharmacology
  • Spectrophotometry
  • Video Recording

Substances

  • Anti-Inflammatory Agents, Non-Steroidal
  • Phenylpropionates
  • loxoprofen
  • Indomethacin