The findings of transfontanelle ultrasonography, undertaken in 36 infants with clinical evidence of central nervous system (CNS) disorders, were compared with the findings of cranial computed tomography (CT). Considering the CT scan findings as gold standard, cranial ultrasonography had a sensitivity of 82 per cent and a specificity of 75 per cent in identifying cerebral pathology. The positive predictive value was 92 per cent and negative predictive value was 45 per cent.