Biological monitoring of occupational exposure to 1-methoxy-2-propanol

J Chromatogr B Biomed Sci Appl. 1997 Jun 20;694(1):93-8. doi: 10.1016/s0378-4347(97)00087-x.

Abstract

At the end of a workweek 23 silkscreen printers gave a urine sample for capillary gas chromatographic analysis for 1,2-propanediol. The mean concentration was 2.52 (S.D. 2.01) mmol mol creatinine(-1) (median=1.76, n=23). The urinary excretion of 1,2-propanediol was linearly dependent on the preceding 1-methoxy-2-propanol exposure measured in the worker's breathing zone [y=0.99+0.28x, n=23, r=0.67, where y is the urinary 1,2-propanediol concentration, in mmol mol creatinine(-1) and x is the concentration, in cm3 m(-3), of 1-methoxy-2-propanol (90.2%), 1-ethoxy-2-propyl acetate (5.8%), 1-methoxy-2-propyl acetate (2.1%) and 1-ethoxy-2-propanol (1.9%) in the air].

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Chromatography, Gas
  • Environmental Monitoring*
  • Humans
  • Occupational Exposure / analysis*
  • Propylene Glycol
  • Propylene Glycols / metabolism*
  • Propylene Glycols / urine*

Substances

  • Propylene Glycols
  • Propylene Glycol
  • propylene glycol methyl ether