Successful birth after intrafallopian transfer of microhatched embryos

Fertil Steril. 1997 Aug;68(2):367-9. doi: 10.1016/s0015-0282(97)81531-2.

Abstract

Objective: To present a successful transfer of microhatched embryos to the fallopian tubes via microlaparoscopy.

Design: Case report.

Setting: Private practice affiliated with a medical university.

Patient: A 40-year-old woman with primary infertility, mildly elevated baseline FSH levels, and a history of poor ovarian response to ovulation induction. Her husband had severe oligoospermia after vasectomy reversal.

Intervention(s): Late luteal leuprolide acetate to pituitary down-regulation followed by pure FSH, 300 IU, and hMG, 300 IU, daily for ovulation induction. Transvaginal oocyte retrieval, intracytoplasmic sperm injection, assisted embryo hatching, microlaparoscopic intrafallopian ET.

Main outcome measure(s): Amniocentesis at the 14th week of gestation revealed a normal karyotype (46,XX), birth of a normal female infant (3700 g).

Result(s): Establishment of a single, viable intrauterine gestation followed by a vaginal delivery at term.

Conclusion(s): This case shows the possibility of using assisted-hatched embryos for laparoscopic intrafallopian tube transfer.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Female
  • Fertilization in Vitro / methods
  • Follicle Stimulating Hormone / therapeutic use
  • Humans
  • Infertility / therapy*
  • Male
  • Menotropins / therapeutic use
  • Microinjections
  • Oligospermia
  • Ovulation Induction
  • Pregnancy
  • Pregnancy Outcome
  • Zygote Intrafallopian Transfer*

Substances

  • Menotropins
  • Follicle Stimulating Hormone