Decreased multi-band posterior interhemispheric coherence with a lipoma on the corpus callosum: a case report of a possible association

Clin Electroencephalogr. 1997 Jul;28(3):155-9. doi: 10.1177/155005949702800307.


The corpus callosum plays a role in mediating interhemisphere communication. Coherence may be a quantitative EEG-based measure of this communication. The present report is of a female schizophrenic patient with a marked coherence deficit in the temporal-parietal-occipital region involving multiple frequency bands. An MRI scan of her brain revealed a lipoma involving the splenium of the corpus callosum. It is speculated that this lipoma may have caused a physical impingment on or developmental aberration of adjacent callosal fibers, resulting in the observed coherence deficit. Further studies of coherence measures in patients with collosal lipomas are proposed.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Brain Mapping
  • Brain Neoplasms / diagnosis
  • Brain Neoplasms / physiopathology*
  • Cerebral Cortex / physiopathology
  • Corpus Callosum / physiopathology*
  • Cortical Synchronization*
  • Dominance, Cerebral / physiology*
  • Electroencephalography*
  • Female
  • Humans
  • Lipoma / diagnosis
  • Lipoma / physiopathology*
  • Magnetic Resonance Imaging
  • Neurocognitive Disorders / diagnosis
  • Neurocognitive Disorders / physiopathology
  • Schizophrenia / diagnosis
  • Schizophrenia / physiopathology
  • Signal Processing, Computer-Assisted