Granulocytic sarcoma of uterine cervix as presentation of acute myeloid leukemia: a case report and review of literature

J Obstet Gynaecol Res. 1997 Jun;23(3):261-6. doi: 10.1111/j.1447-0756.1997.tb00842.x.


Localized extramedullary collection of leukemic cells is termed as granulocytic sarcoma. Incidences of 2-8% in acute myeloid leukemia have been reported in various autopsy studies. In female it usually involves ovary. Since most of such tumors are asymptomatic, they are detected only at autopsy. We report here a case who manifested as abnormal vaginal bleeding, large cervical mass, renal failure, and aspergillous fungaemia. The patient died before she could be treated. From the present report it would appear that granulocytic sarcoma at times may precede other manifestations of leukemia.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Cervix Uteri / diagnostic imaging
  • Cervix Uteri / pathology*
  • Fatal Outcome
  • Female
  • Humans
  • Leukemia, Myeloid / pathology*
  • Leukemia, Myeloid, Acute / diagnosis
  • Leukemia, Myeloid, Acute / pathology*
  • Leukemic Infiltration*
  • Ultrasonography