The detection of major and minor depression in children and adolescents was evaluated in an outpatient sample of 113 children employing the Mood and Feelings Questionnaire (both child and parent versions) and the K-SADS interview. Differences between depressed and nondepressed groups, those with major or minor depression, and depressed children compared with those comorbid for anxiety, were examined. Our findings support the validity of the MFQ as a screening instrument for major and minor depression in a population with a high proportion of depressed cases. High agreement between parent and child ratings was found, with cognitive items being the best predictors of depression.