Spontaneous regression of metastatic renal cancer. Case report and literature review

Am J Clin Oncol. 1997 Aug;20(4):416-8. doi: 10.1097/00000421-199708000-00020.

Abstract

A case of spontaneous regression of pleural and intrapulmonary metastases from renal cell cancer is reported with more than 60 cases reported since the original review of this clinical phenomenon in 1964. The metastatic disease sites are most often pulmonary, but extrapulmonary sites include liver, bone, and CNS regressions. The role of nephrectomy in "spontaneous regression" continues to be obscure, accounting for < 50% of documented cases. Immunologic mechanisms, although intellectually attractive, have not been identified.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adenocarcinoma, Clear Cell / pathology
  • Adenocarcinoma, Clear Cell / surgery
  • Adenoma, Oxyphilic / pathology
  • Adenoma, Oxyphilic / surgery
  • Bone Neoplasms / secondary
  • Carcinoma, Renal Cell / pathology
  • Carcinoma, Renal Cell / secondary*
  • Carcinoma, Renal Cell / surgery
  • Central Nervous System Neoplasms / secondary
  • Follow-Up Studies
  • Humans
  • Kidney Neoplasms / pathology*
  • Kidney Neoplasms / surgery
  • Liver Neoplasms / secondary
  • Lung Neoplasms / pathology
  • Lung Neoplasms / secondary*
  • Male
  • Middle Aged
  • Neoplasm Regression, Spontaneous*
  • Neoplasms, Multiple Primary / pathology
  • Neoplasms, Multiple Primary / surgery
  • Nephrectomy
  • Pleural Neoplasms / pathology
  • Pleural Neoplasms / secondary*