Clinical utility of a newly developed pressure swing adsorption-type oxygen concentrator with a membrane humidifier

Respiration. 1997;64(4):268-72. doi: 10.1159/000196685.


The clinical utility of the newly developed pressure swing adsorption (PSA)-type oxygen concentrator with a membrane humidifier that does not require added water for humidification was evaluated in 13 patients with chronic pulmonary disease who were receiving long-term oxygen therapy. PaO2 and the relative humidity were measured when the patient breathed air and oxygen from the new device via a nasal cannula. After using the new concentrator for 5 h, the patients were asked whether they experienced dry nasal passages or a dry throat. A significant difference between the PaO2 measured while the patients breathed room air and while they breathed oxygen from the new device was observed. A significant difference was observed between the relative humidity of room air (44.7 +/- 18.6%) and that of the oxygen flow (72.7 +/- 14.8%) from the new device. None of the patients experienced dry nasal passages, dry throat, or any other adverse effects. Since this new PSA-type oxygen concentrator with a membrane humidifier supplies well-humidified nasal oxygen without water, laborious cleaning of the container and changing of the water are not necessary, and may help to improve the patient's quality of life.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Aged, 80 and over
  • Equipment Design
  • Female
  • Forced Expiratory Volume
  • Humans
  • Humidity*
  • Lung Diseases, Obstructive / blood
  • Lung Diseases, Obstructive / physiopathology
  • Lung Diseases, Obstructive / therapy*
  • Male
  • Middle Aged
  • Nebulizers and Vaporizers*
  • Oxygen / blood
  • Oxygen Inhalation Therapy / instrumentation*


  • Oxygen