Abstract
Studies of the cellular immunology and protein structure of human and mouse CD1 proteins reveal these to be a family of antigen-presenting molecules that allow T cells to recognize lipid and glycolipid antigens of microbial pathogens.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
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Review
MeSH terms
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Animals
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Antigen Presentation / physiology*
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Antigens, CD1 / metabolism*
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Carbohydrate Sequence
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Humans
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Lipids / chemistry
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Lipids / immunology
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Mice
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Models, Biological
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Molecular Sequence Data
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Molecular Structure
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T-Lymphocytes / immunology