Antigen presentation: mixing oil and water

Curr Biol. 1997 Aug 1;7(8):R508-11. doi: 10.1016/s0960-9822(06)00250-8.

Abstract

Studies of the cellular immunology and protein structure of human and mouse CD1 proteins reveal these to be a family of antigen-presenting molecules that allow T cells to recognize lipid and glycolipid antigens of microbial pathogens.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Antigen Presentation / physiology*
  • Antigens, CD1 / metabolism*
  • Carbohydrate Sequence
  • Humans
  • Lipids / chemistry
  • Lipids / immunology
  • Mice
  • Models, Biological
  • Molecular Sequence Data
  • Molecular Structure
  • T-Lymphocytes / immunology

Substances

  • Antigens, CD1
  • Lipids