Evolution: setting the mutation rate

Curr Biol. 1997 Aug 1;7(8):R487-8. doi: 10.1016/s0960-9822(06)00244-2.


A recent study of X-chromosome and autosome genes in mammals suggests that selective trade-offs are important in the long-term evolution of mutation rates; but recent studies with bacteria show that high mutation rates can nonetheless evolve in the short term in clonal populations.

MeSH terms

  • Animals
  • Bacteria / genetics
  • Biological Evolution*
  • Female
  • Male
  • Mammals
  • Models, Genetic
  • Mutation*
  • Selection, Genetic
  • Time Factors
  • X Chromosome / genetics