Increased recognition of IgA nephropathy in African-American children

Pediatr Nephrol. 1997 Aug;11(4):435-7. doi: 10.1007/s004670050311.


Based upon the percentage of cases of IgA nephropathy (IgAN) in biopsy series, a lower prevalence has been assumed for African-Americans compared with Americans of European descent. This may be due to a racial difference in the basic underlying pathology of IgAN or to racial differences in patterns of referral and biopsy selection practices. Over the past decade (1985-1994), we have found similar incidences of IgAN in Caucasian and African-American children from Shelby County, Tennessee. The incidence was 3.0 cases per million per year for Caucasian and 5.7 cases per million per year for African-American children. IgAN may be more common in African-American children than previously appreciated. Population-based incidence studies will be necessary to determine whether or not our experience has become a more widespread phenomenon.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • African Continental Ancestry Group
  • Child
  • Child, Preschool
  • European Continental Ancestry Group
  • Female
  • Glomerulonephritis, IGA / epidemiology
  • Glomerulonephritis, IGA / ethnology*
  • Humans
  • Incidence
  • Infant
  • Infant, Newborn
  • Male