Paramutation and related allelic interactions

Trends Genet. 1997 Aug;13(8):302-8. doi: 10.1016/s0168-9525(97)01184-0.


Paramutation is an allelic interaction that results in meiotically heritable changes in gene expression. Until recently, the few documented cases in higher plants seemed unusual and rare. This perception is rapidly fading because of the discovery of related examples and the growing recognition of epigenetic changes in a wide variety of biological systems.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Alleles*
  • Animals
  • Anthocyanins / genetics
  • Arabidopsis
  • Drosophila / genetics
  • Drosophila / growth & development
  • Forecasting
  • Gene Expression Regulation*
  • Gene Expression Regulation, Plant
  • Genomic Imprinting
  • Mammals / genetics
  • Mutation*
  • Recombination, Genetic
  • Transgenes
  • Zea mays / genetics*


  • Anthocyanins