Synovial calcification in a patient with collagen-vascular disease: light and electron microscopic studies

J Rheumatol. Autumn 1977;4(3):261-71.


Unusual articular as well as periarticular calcifications are reported in a patient with collagen-vascular disease. Tiny crystals visible in electron micrographs in synovial membrane and in synovial fluid cell vacuoles resemble apatite and appear most consistent with apatite on electron probe studies. The inflammatory synovial effusion also contained chylomicrons. Other joint diseases associated with synovial calcification or suspected synovial apatite are discussed.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Apatites / metabolism
  • Calcinosis / pathology*
  • Collagen Diseases / pathology*
  • Crystallization
  • Female
  • Humans
  • Knee Joint
  • Lipid Metabolism
  • Microscopy, Electron
  • Synovial Fluid / cytology*
  • Synovial Membrane / pathology*
  • Synovial Membrane / ultrastructure
  • Vascular Diseases / pathology*


  • Apatites