Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
, 388 (6643), 639-48

Fossils, Genes and the Evolution of Animal Limbs

Affiliations
Review

Fossils, Genes and the Evolution of Animal Limbs

N Shubin et al. Nature.

Abstract

The morphological and functional evolution of appendages has played a crucial role in the adaptive radiation of tetrapods, arthropods and winged insects. The origin and diversification of fins, wings and other structures, long a focus of palaeontology, can now be approached through developmental genetics. Modifications of appendage number and architecture in each phylum are correlated with regulatory changes in specific patterning genes. Although their respective evolutionary histories are unique, vertebrate, insect and other animal appendages are organized by a similar genetic regulatory system that may have been established in a common ancestor.

Similar articles

See all similar articles

Cited by 134 PubMed Central articles

See all "Cited by" articles

Publication types

LinkOut - more resources

Feedback