Retinal vein occlusion and transient monocular visual loss associated with hyperhomocystinemia

Am J Ophthalmol. 1997 Aug;124(2):257-60. doi: 10.1016/s0002-9394(14)70800-1.


Purpose: To report a 24-year-old man with bilateral central retinal vein occlusions who had preceding episodes of prolonged transient monocular visual loss during which ophthalmoscopic findings were not suggestive of vein occlusion.

Method: Case report.

Result: Extensive hematologic studies for causes of vein occlusion were unremarkable with the exception of increased plasma homocysteine in the patient and in his asymptomatic father.

Conclusions: Impending vein occlusion should be considered in the differential diagnosis of transient monocular visual loss regardless of ophthalmoscopic appearance, and hyperhomocystinemia should be considered as a possible cause of retinal vein occlusion.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Diagnosis, Differential
  • Fundus Oculi
  • Homocystine / blood*
  • Humans
  • Male
  • Retinal Vein Occlusion / diagnosis
  • Retinal Vein Occlusion / etiology*
  • Vision Disorders / diagnosis
  • Vision Disorders / etiology*
  • Vision, Monocular


  • Homocystine