Iris fluorescein angiography in clinical practice

Surv Ophthalmol. Jul-Aug 1997;42(1):41-70. doi: 10.1016/s0039-6257(97)84042-8.


Iris fluorescein angiography is a valuable technique for elucidating a wide range of eye pathologies, among them developmental anomalies, degenerative disease, retinal vascular occlusions, diabetic microangiopathy, uveitis of various etiologies, glaucoma, tumor, and surgical or accidental trauma. In fact, IFA is more sensitive than biomicroscopy in the evaluation of iris abnormalities. Moreover, it provides indirect but reliable information on the retinal circulation when this cannot be examined directly. Some of the most important clinical applications involve the early detection of iris new vessels, cataract management in diabetic patients, and monitoring of iris tumors. Equipment, procedures, and fluorescein angiography patterns in normal and disease states are described and extensively illustrated. More widespread use of this valuable technique is encouraged.

Publication types

  • Review

MeSH terms

  • Animals
  • Fluorescein Angiography / methods*
  • Humans
  • Iris / blood supply*
  • Iris Diseases / diagnosis*
  • Iris Diseases / etiology
  • Sensitivity and Specificity