Cetirizine treatment of allergic cough in children with pollen allergy

Allergy. 1997 Jul;52(7):752-4. doi: 10.1111/j.1398-9995.1997.tb01233.x.


Cetirizine, an antihistamine widely used in the treatment of allergic rhinoconjunctivitis, also has antiallergic activity. The present study aimed to evaluate cetirizine as a treatment for children with allergic cough due to pollen allergy. This was a parallel-group, double-blind, placebo-controlled, randomized study. Twenty children with pollinosis were enrolled: they were subdivided into two groups receiving a 1-month treatment during the pollen season. The following variables were monitored: 1) clinical symptoms and respiratory data (spirometry and PEF) evaluated at baseline and at the end of the study by allergists and by a daily diary card, and 2) pollen count. This study shows that cetirizine treatment reduces cough intensity (P < 0.05) and frequency (P < 0.01). In conclusion, cetirizine does clinically improve cough due to pollen allergy.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial

MeSH terms

  • Adolescent
  • Anti-Allergic Agents / administration & dosage
  • Anti-Allergic Agents / therapeutic use*
  • Cetirizine / administration & dosage
  • Cetirizine / therapeutic use*
  • Child
  • Cough / diagnosis
  • Cough / immunology
  • Double-Blind Method
  • Female
  • Humans
  • Male
  • Peak Expiratory Flow Rate
  • Pollen / immunology
  • Respiratory Hypersensitivity / drug therapy*
  • Spirometry


  • Anti-Allergic Agents
  • Cetirizine