Scedosporium prolificans corneoscleritis: a successful outcome

Aust N Z J Ophthalmol. 1997 May;25(2):169-71. doi: 10.1111/j.1442-9071.1997.tb01301.x.

Abstract

Background: A case of Scedosporium prolificans corneoscleritis is reported in a patient who had developed scleral necrosis following pterygium surgery, with adjunctive beta-irradiation. This fungus has been reported to be the causative organism in only two previous cases of corneoscleritis.

Methods: The patient presented with signs and symptoms typical of corneoscleritis. When the fungus was isolated from a biopsy specimen, aggressive scleral debridement was carried out and intensive antifungal therapy was instigated.

Results: After a prolonged course, the eye was rendered sterile.

Conclusion: Early conjunctival recession and aggressive scleral debridement combined with intensive instillation of antifungals are crucial to the successful management of fungal corneoscleritis.

Publication types

  • Case Reports

MeSH terms

  • Antifungal Agents / therapeutic use
  • Biopsy
  • Cornea / microbiology
  • Cornea / pathology
  • Debridement
  • Eye Infections, Fungal / drug therapy
  • Eye Infections, Fungal / etiology*
  • Eye Infections, Fungal / pathology
  • Humans
  • Keratitis / drug therapy
  • Keratitis / microbiology*
  • Keratitis / pathology
  • Male
  • Middle Aged
  • Mitosporic Fungi* / isolation & purification
  • Mycoses / drug therapy
  • Mycoses / etiology*
  • Mycoses / pathology
  • Necrosis
  • Pterygium / radiotherapy
  • Pterygium / surgery
  • Sclera / microbiology
  • Sclera / pathology
  • Scleritis / drug therapy
  • Scleritis / microbiology*
  • Scleritis / pathology
  • Surgical Wound Infection / drug therapy
  • Surgical Wound Infection / microbiology*
  • Surgical Wound Infection / pathology

Substances

  • Antifungal Agents