Postosteotomy healing in Pyle's disease (familial metaphyseal dysplasia). A case report

Clin Orthop Relat Res. 1997 Aug;(341):215-7.


Pyle's disease is rare skeletal dysplasia in which a defect in metaphyseal remodeling leads to grossly widened metaphyses of long bones. Genu valgum, one of the few clinical findings in this disease, may warrant surgical intervention. Postoperative healing is documented only in Pyle's original patient. A case is presented in which bilateral osteotomies were performed through the proximal tibia for progressive genu valgum. The osteotomies healed within 12 weeks when treatment was performed with standard techniques. This information will allow osteotomies to be performed with confidence.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Bone Diseases, Developmental / complications
  • Bone Diseases, Developmental / diagnostic imaging
  • Bone Diseases, Developmental / surgery*
  • Humans
  • Joint Deformities, Acquired / diagnostic imaging
  • Joint Deformities, Acquired / etiology
  • Joint Deformities, Acquired / surgery*
  • Male
  • Osteotomy*
  • Radiography
  • Tibia / surgery*