Off-loading neuropathic wounds associated with diabetes using an ankle-foot orthosis

J Am Podiatr Med Assoc. 1997 Aug;87(8):349-57. doi: 10.7547/87507315-87-8-349.


Patients with chronic diabetes have a broad spectrum of associated peripheral neurologic deficits that culminate in an increased susceptibility to ulcer formation. The authors focus on the use of the ankle-foot orthosis as both a treatment and a definitive solution for achieving ulcer closure and for minimizing the chance of ulcer recurrence in the ambulatory patient. An analysis of the pathologic forces encountered, and the solution achieved with the ankle-foot orthosis is presented. In addition, the results from a clinical pilot study in subjects with recalcitrant ulcers secondary to Charcot's neuroarthropathy are presented.

Publication types

  • Case Reports

MeSH terms

  • Ankle
  • Connective Tissue / metabolism
  • Diabetes Mellitus, Type 1 / complications*
  • Diabetes Mellitus, Type 1 / metabolism
  • Diabetic Foot / metabolism
  • Diabetic Foot / physiopathology*
  • Diabetic Foot / therapy*
  • Female
  • Foot
  • Glycosylation
  • Humans
  • Male
  • Middle Aged
  • Orthotic Devices*
  • Weight-Bearing*