B-complex vitamins in the prophylaxis and treatment of Wernicke-Korsakoff syndrome

Br J Hosp Med. 1997 May 7-20;57(9):461-5.

Abstract

Wernicke-Korsakoff syndrome, which is associated with high morbidity and mortality, is a more common neuropsychiatric sequela of alcohol misuse than is widely realized. It is easily prevented and treated with parenteral B-complex vitamins, although this treatment is widely under-utilized.

Publication types

  • Review

MeSH terms

  • Ethanol / adverse effects
  • Humans
  • Infusions, Parenteral
  • Intestinal Absorption
  • Substance Withdrawal Syndrome / drug therapy
  • Thiamine Deficiency / drug therapy
  • Vitamin B Complex / administration & dosage
  • Vitamin B Complex / metabolism
  • Vitamin B Complex / therapeutic use*
  • Vitamin B Deficiency / drug therapy
  • Wernicke Encephalopathy / drug therapy*
  • Wernicke Encephalopathy / prevention & control

Substances

  • Vitamin B Complex
  • Ethanol