[Structural characteristics of four long terminal repeats (LTR) of human endogenous retroviruses and features of their integration sites]

Bioorg Khim. 1997 May;23(5):434-40.
[Article in Russian]


Four LTR-containing regions of human chromosome 19 were sequenced by the primer walking technique using strings of short oligonucleotides tightly bound to the template. A comparative and evolutionary analysis of sequences homologous to human endogenous retroviruses (HERV) was performed, and the prototypes of the LTRs were determined. Analysis of the chromosome 19 sequences adjacent to LTR revealed that LTRs of HERV-K share a common location with other retroposons.

Publication types

  • English Abstract

MeSH terms

  • Base Sequence
  • Chromosomes, Human, Pair 19*
  • Cloning, Molecular
  • DNA / genetics
  • DNA, Viral / genetics*
  • Evolution, Molecular
  • Humans
  • Molecular Sequence Data
  • Repetitive Sequences, Nucleic Acid / genetics*
  • Retroviridae / genetics*
  • Sequence Alignment
  • Sequence Analysis, DNA


  • DNA, Viral
  • DNA