Fatal anaphylactic reaction to hair dye

Am J Forensic Med Pathol. 1997 Sep;18(3):290-2. doi: 10.1097/00000433-199709000-00012.


We present the first reported case of fatal anaphylaxis resulting from the application of hair dye. A 68-year-old woman had a history of anaphylactic reaction to hair dye 2 years before her death. After using a different hair dye preparation, the patient experienced shortness of breath, collapsed, and died. Autopsy findings were consistent with anaphylaxis. Pathogenic mechanisms are reviewed.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Anaphylaxis / chemically induced*
  • Anaphylaxis / immunology
  • Autopsy
  • Fatal Outcome
  • Female
  • Hair Dyes / adverse effects*
  • Humans
  • Phenylenediamines / adverse effects*
  • Phenylenediamines / immunology


  • Hair Dyes
  • Phenylenediamines