Coronary calcium measurements by double helical computed tomography. Using the average instead of peak density algorithm improves reproducibility

Invest Radiol. 1997 Sep;32(9):503-6. doi: 10.1097/00004424-199709000-00001.


Rationale and objectives: Coronary calcium (CC) measured by fast computed tomography (CT) was proposed recently as a noninvasive method of monitoring the coronary atherosclerotic process. Assessment of the reproducibility of CC measurements (mainly interstudy variability) is essential for consistent interpretation of serial studies.

Methods: The authors scanned 74 patients (50 men and 24 women) twice on the same day to determine the interstudy variability of a new scoring algorithm, using the average instead of conventional peak CT density values.

Results: Nineteen patients had no calcium on either scan. In the remaining 55 patients, interstudy variability was decreased by 31% using the average algorithm (32%-23%; P < 0.001).

Conclusions: Using the average instead of conventional peak density score provides better reproducible measurements of calcium by double helical CT.

MeSH terms

  • Adult
  • Aged
  • Algorithms
  • Calcinosis / diagnostic imaging*
  • Coronary Angiography / methods
  • Coronary Artery Disease / diagnostic imaging*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Observer Variation
  • Reproducibility of Results
  • Tomography, X-Ray Computed / methods*