False-negative fluorine-18-FDG PET in metastatic carcinoid

J Nucl Med. 1997 Sep;38(9):1382-3.

Abstract

Carcinoid tumors have high numbers of somatostatin receptors that allow scintigraphic imaging with the radiolabeled somatostatin analog octreotide. Experience, however, with PET using 2-[18F]fluoro-2-deoxy-D-glucose (18FDG) in carcinoid is very limited. In two prior studies which investigated the utility of 18FDG-PET in cancer detection, three patients with small, solitary, indolent carcinoid tumors had false-negative results. We report a case where 18FDG-PET imaging was false-negative in a patient with known metastatic carcinoid and a positive octreotide scan.

Publication types

  • Case Reports

MeSH terms

  • Carcinoid Tumor / complications
  • Carcinoid Tumor / diagnostic imaging*
  • Carcinoid Tumor / secondary*
  • Deoxyglucose / analogs & derivatives*
  • False Negative Reactions
  • Fluorine Radioisotopes*
  • Fluorodeoxyglucose F18
  • HIV Seropositivity / complications*
  • Humans
  • Ileal Neoplasms / complications
  • Ileal Neoplasms / diagnostic imaging
  • Liver Neoplasms / complications
  • Liver Neoplasms / diagnostic imaging*
  • Liver Neoplasms / secondary
  • Male
  • Middle Aged
  • Radiopharmaceuticals*
  • Tomography, Emission-Computed*

Substances

  • Fluorine Radioisotopes
  • Radiopharmaceuticals
  • Fluorodeoxyglucose F18
  • Deoxyglucose