Update on antifungal resistance

Trends Microbiol. 1997 Sep;5(9):372-5. doi: 10.1016/S0966-842X(97)01108-6.


Overuse of antifungal agents has resulted in the selection of naturally resistant Candida species, as well as expression of resistance from previously susceptible species resulting from genetic mutations and/or selection of resistant subpopulations. Strategies for the appropriate use of antifungal agents need to be developed to prevent further development of resistance.

Publication types

  • Review

MeSH terms

  • Antifungal Agents / therapeutic use*
  • Candida / genetics
  • Candida / pathogenicity
  • Candidiasis / drug therapy*
  • Drug Resistance, Microbial*
  • Drug Therapy / methods
  • Fungi / genetics
  • Fungi / pathogenicity
  • Humans
  • Mutation
  • Mycoses / drug therapy*


  • Antifungal Agents