Elevated levels of circulating soluble adhesion molecules in peripheral blood of patients with unstable angina

Am J Cardiol. 1997 Sep 1;80(5):617-9. doi: 10.1016/s0002-9149(97)00432-3.


We have demonstrated increased levels of the circulating soluble adhesion molecules (sCAMs), ICAM-1, VCAM-1, and E-selectin in patients with unstable angina compared with healthy controls. Our findings support the role of inflammation in clinically unstable coronary disease, and may indicate a potential role for measurement of peripheral sICAM levels as a marker for inflammatory activity in atherosclerotic plaque.

MeSH terms

  • Adult
  • Angina Pectoris / blood
  • Angina, Unstable / blood*
  • Chest Pain / blood
  • Coronary Artery Disease / blood
  • E-Selectin / blood*
  • Female
  • Humans
  • Intercellular Adhesion Molecule-1 / blood*
  • Male
  • Middle Aged
  • Vascular Cell Adhesion Molecule-1 / blood*


  • E-Selectin
  • Vascular Cell Adhesion Molecule-1
  • Intercellular Adhesion Molecule-1