Use of a C-arm system to generate true three-dimensional computed rotational angiograms: preliminary in vitro and in vivo results

AJNR Am J Neuroradiol. 1997 Sep;18(8):1507-14.


Purpose: To evaluate the potential use of a C-arm mounted X-ray image intensifier (XRII) system to generate three-dimensional computed rotational angiograms during interventional neuroradiologic procedures.

Methods: A clinical angiographic system was modified to allow collection of sufficient views during selective intraarterial contrast injections for CT reconstruction of a 15 x 15 x 15-cm3 volume. Image intensifier distortion and C-arm instabilities were corrected by using image-based techniques. The impact of the pulsatile nature of the vessels during image data acquisition and of the presence of bone on the 3-D reconstructions was investigated by generating 3-D reconstructions of an anesthetized 20-kg pig and of a human skull phantom.

Results: A sequence of images sufficient for 3-D reconstruction was acquired in less than 5 seconds. Image intensifier distortion and C-arm instabilities were corrected to subpixel accuracy (0.035 mm and 0.07 mm, respectively). Both the intracranial vessels of the pig and the small, high-contrast structures in the skull were reconstructed with negligible artifacts.

Conclusions: Using a C-arm mounted XRII system, computed rotational angiography can provide true 3-D images of diagnostic quality.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Artifacts
  • Brain / blood supply*
  • Carotid Stenosis / diagnostic imaging
  • Cerebral Angiography / instrumentation*
  • Humans
  • Image Processing, Computer-Assisted / instrumentation*
  • In Vitro Techniques
  • Phantoms, Imaging
  • Sensitivity and Specificity
  • Swine
  • Tomography, X-Ray Computed / instrumentation*
  • X-Ray Intensifying Screens*