Extradural buprenorphine suppresses breast feeding after caesarean section

Br J Anaesth. 1997 Jul;79(1):120-1. doi: 10.1093/bja/79.1.120.

Abstract

Satisfactory pain relief with postoperative extradural bupivacaine increases the amount of breast feeding after Caesarean section. To investigate the effect of extradural buprenorphine, we have evaluated the amount of breast feeding and the gain in infant weight for 11 days after Caesarean section in patients who received continuous extradural bupivacaine with or without buprenorphine. Extradural buprenorphine significantly decreased both measures although there was no significant difference in pain intensity. We suggest that extradural buprenorphine suppressed breast feeding after Caesarean section.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Analgesia, Epidural
  • Analgesics, Opioid / administration & dosage
  • Analgesics, Opioid / pharmacology*
  • Breast Feeding*
  • Bupivacaine / pharmacology
  • Bupivacaine / therapeutic use
  • Buprenorphine / administration & dosage
  • Buprenorphine / pharmacology*
  • Cesarean Section*
  • Feeding Behavior / drug effects
  • Female
  • Humans
  • Infant, Newborn
  • Pain, Postoperative / prevention & control*
  • Pregnancy
  • Weight Gain / drug effects

Substances

  • Analgesics, Opioid
  • Buprenorphine
  • Bupivacaine