Abstract
Immunobiological properties of human specific transfer factor (TF) to Staphylococcus aureus antigens were studied. It is shown that this TF activated human leucocytes in vitro as well as in vivo. Antigen specificity of TF's immunomodulating effects is also shown. In vitro we used leucocyte migration inhibition test (IML), macrophage inhibition test (MPI) and rosette formation (E-ros). For testing in vivo we used delayed type hypersensitivity (DTH) skin tests.
Publication types
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Comparative Study
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English Abstract
MeSH terms
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Animals
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Antigens, Bacterial / immunology*
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Blood Donors
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Cell Migration Inhibition
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Epitopes / drug effects
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Epitopes / immunology
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Guinea Pigs
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Humans
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Hypersensitivity, Delayed / immunology
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Immunization / methods
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Lymphocyte Activation / drug effects
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Lymphocyte Activation / immunology
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Rosette Formation
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Species Specificity
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Staphylococcal Protein A / immunology
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Staphylococcus aureus / immunology*
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Transfer Factor / immunology*
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Transfer Factor / pharmacology
Substances
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Antigens, Bacterial
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Epitopes
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Staphylococcal Protein A
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Transfer Factor