The authors present one personal case of paraurethral acquired cyst (Skene's cyst) during pregnancy, presenting symptoms of micturitional obstruction. Clinical behaviour during pregnancy, labour induction and surgical ablation of the cyst during puerperium are illustrated. Differential diagnosis is analyzed. The advantages of proposed surgical techniques are discussed: agobiopsy, marsupialization, surgical ablation. Eventually the authors determine which is the most suitable therapeutic option during pregnancy.