Intracranial intraparenchymal schwannoma: report of three cases

Acta Neurochir (Wien). 1997;139(8):756-60. doi: 10.1007/BF01420049.


Intracranial intraparenchymal schwannomas are rare. We report three patients with an intracranial intraparenchymal schwannoma and discuss the clinical and neuroradiological aspects of this particular tumour. The patients were a 21-year-old male, a 64-year-old female and a 17-year-old male. The tumours were located in cerebrum in two patients and the cerebellum in one patient. Computerized tomography (CT) scans demonstrated a slightly high density area with homogeneous enhancement by contrast medium. Magnetic resonance imaging (MRI) showed slightly low signal intensity on the T1-weighted image, high or mixed signal intensity on the T2-weighted image and homogeneous enhancement by gadolinium diethylene triamine penta-acetic acid (Gd-DTPA). Radiological studies revealed cystic components in 2 of the 3 patients. All tumours were firm, well-demarcated, and completely removed. The diagnosis of schwannoma was derived from histological and immunohistochemical studies in all 3 cases; 2 cases were also examined by electron microscopy.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Adult
  • Brain / pathology
  • Brain / surgery
  • Brain Neoplasms / diagnosis
  • Brain Neoplasms / pathology
  • Brain Neoplasms / surgery*
  • Cerebellar Neoplasms / diagnosis
  • Cerebellar Neoplasms / pathology
  • Cerebellar Neoplasms / surgery*
  • Cerebellum / pathology
  • Cerebellum / surgery
  • Contrast Media
  • Female
  • Gadolinium DTPA
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Neurilemmoma / diagnosis
  • Neurilemmoma / pathology
  • Neurilemmoma / surgery*
  • Tomography, X-Ray Computed


  • Contrast Media
  • Gadolinium DTPA