Epidemiology of columnar-lined esophagus and adenocarcinoma

Gastroenterol Clin North Am. 1997 Sep;26(3):487-94. doi: 10.1016/s0889-8553(05)70308-3.


Barrett's esophagus is found in about 1% of the older population and in 3% to 5% of persons with gastroesophageal reflux. It is acquired more commonly by men and the prevalence increases with age. Most cases in the population remain undiagnosed. The incidence of adenocarcinoma of the esophagus and esophagogastric junction is increasing, both being related to Barrett's esophagus. Small areas of intestinal metaplasia are common but of uncertain significance.

Publication types

  • Review

MeSH terms

  • Adenocarcinoma / epidemiology*
  • Adult
  • Age Factors
  • Aged
  • Barrett Esophagus / epidemiology*
  • Esophageal Neoplasms / epidemiology*
  • Female
  • Gastroesophageal Reflux / epidemiology
  • Humans
  • Incidence
  • Male
  • Middle Aged
  • Prevalence
  • Risk Factors
  • Sex Factors