Bile reflux in columnar-lined esophagus

Gastroenterol Clin North Am. 1997 Sep;26(3):565-82. doi: 10.1016/s0889-8553(05)70314-9.


Barrett's esophagus represents a metaplastic process in which the normal squamous epithelium of the lower esophagus is replaced by metaplastic columnar epithelium. Although the role of acid and pepsin in the development of Barrett's esophagus is well accepted, the importance of duodenogastroesophageal reflux in this disorder is not clear.

Publication types

  • Review

MeSH terms

  • Barrett Esophagus / complications*
  • Bile Reflux / complications*
  • Bile Reflux / diagnosis
  • Duodenogastric Reflux / complications
  • Duodenogastric Reflux / diagnosis
  • Gastroesophageal Reflux / complications
  • Humans
  • Monitoring, Ambulatory