Bovine attaching and effacing Escherichia coli possess a pathogenesis island related to the LEE of the human enteropathogenic Escherichia coli strain E2348/69

FEMS Microbiol Lett. 1997 Sep 15;154(2):415-21. doi: 10.1111/j.1574-6968.1997.tb12676.x.


Attaching and effacing Escherichia coli (AEEC) has been described as a cause of diarrhea in calves. The molecular pathogenesis of AEEC was mainly studied in human enteropathogenic E. coli strain E2348/69 in which the virulence correlated with the presence of a 35.4 kb pathogenesis island called LEE. We showed that several strains isolated from calves with diarrhea were able to produce attaching and effacing lesions in a rabbit ileal loop model and that they possess a pathogenesis island related to the LEE. Moreover, we showed that the LEE from bovine strains was inserted mainly at a different position in the chromosome compared to the human enteropathogenic E. coli strain E2348/69.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cattle
  • Cattle Diseases / microbiology*
  • Chromosome Mapping
  • Diarrhea / microbiology*
  • Diarrhea / veterinary
  • Escherichia coli / pathogenicity*
  • Humans
  • Polymerase Chain Reaction
  • Rabbits