Olive oil increases the magnitude of postprandial chylomicron remnants compared to milk fat and safflower oil

J Am Coll Nutr. 1997 Oct;16(5):429-34. doi: 10.1080/07315724.1997.10718709.

Abstract

Objective: The acute effects of olive oil, milk fat and safflower oil on postprandial lipemia and remnant lipoprotein metabolism were investigated.

Methods: Eight Healthy male volunteers randomly underwent three types of oral fat-vitamin A loading tests. The test drink was a mixture of retinyl palmitate (RP)(50,000 IU of aqueous vitamin A/m2 body surface area) and one of the three types of oils (40 g of fat/m2 body surface area): olive oil (70.7% oleic acid of total fatty acids); milk fat (69.3% saturated fatty acid); safflower oil (74.2% linoleic acid).

Results: Olive oil significantly increased plasma triacylglycerol and RP concentrations 4 hours after fat loading, as compared to other fats. Increases of remnant like particle concentrations were higher after olive oil than after the other two fats.

Conclusion: These results show that olive oil increases the magnitude of postprandial chylomicrons and chylomicron remnants compared to milk fat and safflower oil.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Animals
  • Chylomicrons / metabolism*
  • Dietary Fats, Unsaturated / administration & dosage
  • Dietary Fats, Unsaturated / pharmacology*
  • Food
  • Humans
  • Kinetics
  • Lipids / administration & dosage
  • Lipids / pharmacology*
  • Male
  • Milk / chemistry*
  • Olive Oil
  • Plant Oils / administration & dosage
  • Plant Oils / pharmacology*
  • Safflower Oil / administration & dosage
  • Safflower Oil / pharmacology*
  • Triglycerides / blood

Substances

  • Chylomicrons
  • Dietary Fats, Unsaturated
  • Lipids
  • Olive Oil
  • Plant Oils
  • Triglycerides
  • Safflower Oil