Invasive soft tissue infections with Streptococcus pneumoniae in patients with systemic lupus erythematosus: case report and review of the literature

Arthritis Rheum. 1997 Sep;40(9):1716-9. doi: 10.1002/art.1780400924.


Pneumococcal infections of the soft tissues are uncommon. However, patients with systemic lupus erythematosus (SLE) may be predisposed to this condition, perhaps by virtue of hypocomplementemia and low, nonprotective concentrations of antipneumococcal antibodies. We report a case of severe cellulitis and fasciitis of the anterior neck in a young woman with SLE. The literature on SLE and pneumococcal soft tissue infections is reviewed. A clinical syndrome of SLE and pneumococcal soft-tissue infections of the neck and pharynx is described.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Cellulitis / microbiology*
  • Fasciitis / microbiology*
  • Female
  • Humans
  • Immunocompromised Host
  • Lupus Erythematosus, Systemic / complications*
  • Pneumococcal Infections / etiology*
  • Soft Tissue Infections / etiology*
  • Streptococcus pneumoniae / isolation & purification