[Direct carotid-cavernous fistula. Clinical, radiologic and therapeutic studies. Apropos of 49 cases]

J Neuroradiol. 1997 Aug;24(2):141-54.
[Article in French]


Materials and methods: From 1977 to 1996, 49 direct carotido-cavernous fistulae were studied among the sixty some cases diagnosed over these 20 years. Five were caused by spontaneous rupture of an intracavernous aneurysm and the others were caused by trauma.

Results: The clinical presentation in 37 patients was exophthalmia with pulsating conjunctival hyperhemia and vascular murmur. Some cases had a neurological syndrome suggesting cavernous involvement. A bilateral presentation was observed in 2 cases. One patient had no ophthalmologic syndrome but had a vascular murmur. Prior to 1982, all patients were treated and cured by occlusion of the internal carotid after direct access via the neck using a 3 F Fogarty catheter. Since 1982, patients have been treated with the detachable balloon technique. The carotid was preserved in 16 cases. In one case, secondary thrombosis occurred due to major dissection. In one case, the size of the breach was too small for the balloon so a coil was used. In one other case, insertion of the guide wire and catheter was sufficient to occlude the fistula. There was one death during treatment due to fistula rupture and one partially regressive right hemiplegia which could not be explained. This patient also developed left hemiplegia two years later, again with no explaining cause. Cure was achieved in the other patients without sequellae.

Discussion: Direct carotido-cavernous fistulae due to rupture of an aneurysm or trauma are uncommon. When flow through the breach is minimal, vascular treatment may not be necessary unless clinical signs appear since this type of fistula heals spontaneously. In other cases, an endovascular balloon procedure is indicated. There are few complications. Embolization with coils or other devices should only be used in selected cases when the breach is too small for the balloon.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aneurysm, Dissecting / complications
  • Aneurysm, Ruptured / complications
  • Arteriovenous Fistula / diagnostic imaging
  • Arteriovenous Fistula / etiology
  • Arteriovenous Fistula / pathology*
  • Arteriovenous Fistula / therapy
  • Carotid Arteries / diagnostic imaging
  • Carotid Arteries / pathology*
  • Catheterization / instrumentation
  • Cause of Death
  • Cavernous Sinus / diagnostic imaging
  • Cavernous Sinus / pathology*
  • Conjunctival Diseases / pathology
  • Craniocerebral Trauma / complications
  • Embolization, Therapeutic / instrumentation
  • Embolization, Therapeutic / methods
  • Exophthalmos / pathology
  • Female
  • Follow-Up Studies
  • Hemiplegia / etiology
  • Humans
  • Hyperemia / pathology
  • Intracranial Aneurysm / complications
  • Male
  • Middle Aged
  • Radiography
  • Rupture, Spontaneous
  • Thrombosis / etiology
  • Treatment Outcome
  • Wound Healing