Acute renal failure due to indinavir crystalluria and nephrolithiasis: report of two cases

Am J Kidney Dis. 1997 Oct;30(4):558-60. doi: 10.1016/s0272-6386(97)90316-4.

Abstract

Two patients with oliguric acute renal failure (ARF) attributed to crystalluria and nephrolithiasis with obstructive uropathy caused by the human immunodeficiency virus protease inhibitor indinavir are described. In both patients, ARF resolved with administration of intravenous fluids. One patient required urologic intervention to relieve bilateral ureteral obstruction.

Publication types

  • Case Reports

MeSH terms

  • Acute Kidney Injury / chemically induced*
  • Acute Kidney Injury / therapy
  • Acute Kidney Injury / urine
  • Adult
  • Crystallization
  • Fluid Therapy
  • HIV Infections / drug therapy*
  • HIV Protease Inhibitors / adverse effects*
  • HIV Protease Inhibitors / therapeutic use
  • Humans
  • Indinavir / adverse effects*
  • Indinavir / therapeutic use
  • Kidney Calculi / chemically induced*
  • Kidney Calculi / therapy
  • Kidney Calculi / urine
  • Male

Substances

  • HIV Protease Inhibitors
  • Indinavir