Automated detection of local artery wall thickness based on M-line signal processing

Ultrasound Med Biol. 1997;23(7):1017-23. doi: 10.1016/s0301-5629(97)00119-1.


The Young's modulus of an arterial segment, a measure of the elastic properties of the arterial wall, requires the simultaneous and local assessment of pulse pressure, wall thickness, diameter, and distensibility (relative increase in cross-sectional area per change in blood pressure). The diameter and relative increase in cross-sectional area can be obtained with a wall track system, processing the radiofrequency (r.f.) ultrasound signals received along a single line of observation (M-line processing). It will be demonstrated that it is feasible to combine, in a single measurement, the assessment of wall thickness and the (relative change in) diameter involving a minimum of user interaction. Phantom tests show a standard error of the estimate for intima-media thickness measurements of less than 20 microns; in vivo registrations exhibit a variation on the order of 45 microns. It is concluded that processing of the radiofrequency ultrasound signal, acquired along an M-line, provides an accurate and time-efficient alternative for videoprocessing of 2-dimensional B-mode ultrasound images to estimate artery wall thickness.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Algorithms
  • Carotid Artery, Common / diagnostic imaging*
  • Carotid Artery, Common / physiology
  • Elasticity
  • Female
  • Humans
  • Linear Models
  • Phantoms, Imaging
  • Signal Processing, Computer-Assisted*
  • Ultrasonography