Leukocyte adhesion: CD11/CD18 integrins and intercellular adhesion molecules

Curr Opin Cell Biol. 1997 Oct;9(5):643-50. doi: 10.1016/s0955-0674(97)80117-2.


Leukocyte integrins and intercellular adhesion molecules play pivotal roles in leukocyte adhesion to target cells and extracellular matrices. Recently, novel intercellular adhesion molecules have been identified, and much information has been obtained on the structures and binding sites of leukocyte integrins and of intercellular adhesion molecules. Furthermore, much progress has been made in the study of integrin activation and the role of leukocyte adhesion molecules in disease.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • CD18 Antigens / physiology
  • Cell Adhesion / physiology*
  • Cell Adhesion Molecules / physiology*
  • Humans
  • Integrins / physiology*
  • Leukocytes / cytology*
  • Lymphocyte Function-Associated Antigen-1 / physiology


  • CD18 Antigens
  • Cell Adhesion Molecules
  • Integrins
  • Lymphocyte Function-Associated Antigen-1