Chromosomal anomalies in a case of proliferative myositis

E N McComb; J R Neff; S L Johansson; M Nelson; J A Bridge

doi:10.1016/s0165-4608(96)00428-1

Chromosomal anomalies in a case of proliferative myositis

Cancer Genet Cytogenet. 1997 Oct 15;98(2):142-4. doi: 10.1016/s0165-4608(96)00428-1.

Authors

E N McComb¹, J R Neff, S L Johansson, M Nelson, J A Bridge

Affiliation

¹ Department of Orthopaedic Surgery, University of Nebraska Medical Center, Omaha 68198-5440, USA.

PMID: 9332481
DOI: 10.1016/s0165-4608(96)00428-1

Abstract

Proliferative myositis, a reactive lesion similar to proliferative fasciitis and nodular fasciitis, has only been cytogenetically described in one other report to date. This previously described case showed trisomy 2. Cytogenetic analysis and fluorescence in situ hybridization (FISH) of a proliferative myositis lesion in the present study did not reveal trisomy 2 but the following clonal translocation was observed: 46,XX,t(6;14)(q23;q32).

Publication types

Case Reports

MeSH terms

Chromosomes, Human, Pair 14*
Chromosomes, Human, Pair 6*
Female
Humans
In Situ Hybridization, Fluorescence
Karyotyping
Middle Aged
Myositis / genetics*
Myositis / pathology
Translocation, Genetic*