Disseminated infection due to Bipolaris australiensis in a young immunocompetent man: case report and review

Clin Infect Dis. 1997 Aug;25(2):311-3. doi: 10.1086/514528.


We report a case of disseminated infection due to Bipolaris australiensis in a 21-year-old immunocompetent Pakistani man. He presented with fever and jaundice. Examination revealed a mass in the right lung, mediastinal lymphadenopathy, a pericardial effusion, and abdominal masses obstructing and invading the common bile duct and right ureter. Histological examination and culture of a biopsy specimen of the hilar mass yielded the fungal pathogen B. australiensis. The patient was treated successfully with amphotericin B and itraconazole.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Amphotericin B / therapeutic use
  • Antifungal Agents / therapeutic use
  • Cholestasis / microbiology
  • Drug Therapy, Combination
  • Humans
  • Itraconazole / therapeutic use
  • Lung Diseases, Fungal / microbiology
  • Lymphatic Diseases / microbiology
  • Male
  • Mediastinal Diseases / microbiology
  • Mitosporic Fungi / growth & development
  • Mitosporic Fungi / isolation & purification*
  • Mycoses / diagnosis*
  • Mycoses / drug therapy
  • Pericardial Effusion / microbiology
  • Ureteral Obstruction / microbiology


  • Antifungal Agents
  • Itraconazole
  • Amphotericin B