Activity of SCH 56592 compared with those of fluconazole and itraconazole against Candida spp

Antimicrob Agents Chemother. 1997 Oct;41(10):2310-1. doi: 10.1128/AAC.41.10.2310.

Abstract

The in vitro activity of Schering 56592, a new azole drug, was compared with those of fluconazole and itraconazole against 103 isolates of Candida comprising 10 different species. Schering 56592 was more active than itraconazole and fluconazole, and it was active against many fluconazole-resistant isolates.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antifungal Agents / pharmacology*
  • Candida / drug effects*
  • Candidiasis / microbiology
  • Fluconazole / pharmacology*
  • Itraconazole / pharmacology*
  • Microbial Sensitivity Tests
  • Triazoles / pharmacology*

Substances

  • Antifungal Agents
  • Triazoles
  • Itraconazole
  • posaconazole
  • Fluconazole