Pyronaridine for treatment of Plasmodium ovale and Plasmodium malariae infections

Antimicrob Agents Chemother. 1997 Oct;41(10):2317-9. doi: 10.1128/AAC.41.10.2317.

Abstract

The clinical efficacy of oral pyronaridine was assessed in 22 symptomatic Cameroonian patients infected with Plasmodium ovale or Plasmodium malariae. All patients were cured on or before day 4. In vitro drug assays confirmed the sensitivity of P. ovale and P. malariae isolates to chloroquine and pyronaridine.

Publication types

  • Clinical Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Animals
  • Antimalarials / administration & dosage
  • Antimalarials / therapeutic use*
  • Child
  • Female
  • Humans
  • Malaria / drug therapy*
  • Malaria / parasitology
  • Male
  • Naphthyridines / administration & dosage
  • Naphthyridines / therapeutic use*
  • Plasmodium malariae*
  • Plasmodium*
  • Tablets, Enteric-Coated

Substances

  • Antimalarials
  • Naphthyridines
  • Tablets, Enteric-Coated
  • pyronaridine