Lack of Clinical Significance for the Common Arginine-To-Leucine Substitution at Codon 463 of the katG Gene in Isoniazid-Resistant Mycobacterium Tuberculosis in Singapore

J Infect Dis. 1997 Oct;176(4):1125-7. doi: 10.1086/517320.

Publication types

  • Comment
  • Letter

MeSH terms

  • Antitubercular Agents / pharmacology
  • Arginine / genetics
  • Bacterial Proteins*
  • Drug Resistance, Microbial / genetics*
  • Humans
  • Isoniazid / pharmacology
  • Leucine / genetics
  • Molecular Epidemiology
  • Mutagenesis, Site-Directed
  • Mycobacterium / genetics
  • Mycobacterium tuberculosis / drug effects
  • Mycobacterium tuberculosis / genetics*
  • Peroxidases / genetics*
  • Point Mutation
  • Singapore / epidemiology
  • Tuberculosis / drug therapy*
  • Tuberculosis / epidemiology
  • Tuberculosis / genetics

Substances

  • Antitubercular Agents
  • Bacterial Proteins
  • Arginine
  • Peroxidases
  • catalase HPI
  • Leucine
  • Isoniazid