Idiopathic hypertrophic pachymeningitis: spectrum of the disease

Neuroradiology. 1997 Sep;39(9):619-23. doi: 10.1007/s002340050479.


Hypertrophic pachymeningitis is extremely rare. It is a fibrosing inflammatory process which involves the dura mater, including the tentorium. Numerous pathological entities produce thickening of the pachymeninges, so that idiopathic hypertrophic pachymeningitis is a diagnosis of exclusion. We describe four patients with idiopathic hypertrophic pachymeningitis who had varied clinical presentation. Imaging studies revealed diffuse thickening of the pachymeninges; in one patient there was extensive dural sinus thrombosis. Since no identifiable cause was found, the cases were labelled as idiopathic.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Brain / pathology
  • Cranial Sinuses / pathology
  • Diagnosis, Differential
  • Dura Mater / pathology
  • Female
  • Humans
  • Hypertrophy
  • Magnetic Resonance Imaging*
  • Male
  • Meningitis / diagnosis*
  • Meningitis / pathology
  • Middle Aged
  • Neurologic Examination
  • Sinus Thrombosis, Intracranial / diagnosis
  • Sinus Thrombosis, Intracranial / pathology
  • Tomography, X-Ray Computed*