The application of the macular photocoagulation study eligibility criteria for laser treatment in age-related macular degeneration

Ophthalmic Surg Lasers. 1997 Oct;28(10):823-7.


Background and objective: To analyze the application of the Macular Photocoagulation Study eligibility criteria for laser photocoagulation of choroidal neovascularization, in view of the expansion of these criteria in recent years.

Patients and methods: The authors prospectively analyzed 50 eyes of 47 consecutive patients with exudative age-related macular degeneration (AMD) to determine their suitability for treatment.

Results: Fifteen eyes (30%) were found to be suitable for laser photocoagulation. Patients eligible for treatment were more likely to have experienced visual symptoms for a months or less (P = .006), to have a visual acuity of 20/200 or better (P = .009), and to be younger in age (P = .02). Visual symptoms experienced for a month or less were more prevalent in extrafoveal exudative lesions compared with the subfoveal type (P = .01)

Conclusions: Despite recent advances, laser photocoagulation still can be applied only to a minority of the patients with neovascular AMD. Prompt ocular examination following the onset of visual symptoms is essential.

Publication types

  • Comparative Study

MeSH terms

  • Aged
  • Aged, 80 and over
  • Choroid / blood supply
  • Eligibility Determination*
  • Exudates and Transudates
  • Female
  • Fluorescein Angiography
  • Fundus Oculi
  • Humans
  • Laser Coagulation*
  • Macula Lutea / pathology
  • Macula Lutea / surgery*
  • Macular Degeneration / complications
  • Macular Degeneration / diagnosis
  • Macular Degeneration / surgery*
  • Male
  • Middle Aged
  • Neovascularization, Pathologic / complications
  • Neovascularization, Pathologic / diagnosis
  • Neovascularization, Pathologic / surgery
  • Prospective Studies
  • Treatment Outcome
  • Visual Acuity