A neurologist's perspective on the aging brain

Arch Neurol. 1997 Oct;54(10):1211-4. doi: 10.1001/archneur.1997.00550220023008.


I have worked as a neurologist in old age homes and chronic hospitals for 30 years, and over this period I have seen thousands of older patients with dementias and other degenerative neurological syndromes. A high proportion of these patients have steadily and sometimes rapidly advancing dementias of the type we now tend to call Alzheimer disease (AD) (although this term was used in a much narrower sense when I started seeing such patients in the mid-sixties).

MeSH terms

  • Aging / physiology*
  • Alzheimer Disease / physiopathology*
  • Alzheimer Disease / psychology*
  • Brain / physiopathology*
  • Humans